Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536100 | 0.82 | LMNA (0.54) | L3MBTL1LMNASMN1; SMN2HSD17B10MCL1 | |
| SCHEMBL22660224 | 0.79 | LMNA (0.49) | L3MBTL1LMNATSHRPRSS1PTGDR2 | |
| SCHEMBL16193425 | 0.79 | TSHR (0.50) | TSHRRAB9AFFAR1FFAR4PDK2 | |
| SCHEMBL10791590 | 0.79 | USP2 (0.57) | L3MBTL1LMNAATMTSHRPRSS1 | |
| SCHEMBL17823298 | 0.76 | CYP1A2 (0.43) | ATMUSP2SMN1; SMN2 | |
| SCHEMBL11074707 | 0.76 | MEN1 (0.44) | L3MBTL1LMNAATMNPC1RAB9A | |
| SCHEMBL13282757 | 0.76 | PTGDR2 (0.57) | LMNATSHRPTGDR2RAB9ASMN1; SMN2 | |
| SCHEMBL7523915 | 0.76 | TSHR (0.58) | L3MBTL1LMNAATMTSHRPRSS1 | |
| SCHEMBL25586358 | 0.76 | PTGDR2 (0.48) | L3MBTL1LMNATSHRPRSS1PTGDR2 | |
| Hydrochloric Acid SCHEMBL11068575 | 0.74 | MEN1 (0.47) | LMNAATMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |