Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 12/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26853210 | 1.00 | PREP (0.51) | PREPPSMB5FAPF2 | |
| SCHEMBL21156212 | 0.93 | PREP (0.48) | PREPPSMB5FAPF2 | |
| SCHEMBL26853284 | 0.93 | PREP (0.48) | PREPPSMB5FAPF2 | |
| SCHEMBL8234287 | 0.88 | PREP (0.56) | PREPPSMB5FAPF2 | |
| SCHEMBL16079844 | 0.86 | PREP (0.55) | PREPPSMB5FAPF2 | |
| SCHEMBL24025130 | 0.85 | PREP (0.54) | PREPPSMB5FAPF2 | |
| SCHEMBL21156219 | 0.85 | PREP (0.54) | PREPPSMB5FAPF2 | |
| SCHEMBL14161094 | 0.85 | PREP (0.54) | PREPPSMB5FAP | |
| SCHEMBL14161093 | 0.85 | PREP (0.54) | PREPPSMB5FAP | |
| SCHEMBL12658549 | 0.85 | PREP (0.53) | PREPPSMB5FAPF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583516-B2 | Dash inhibitors, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210353652-A1 | TUMOR MICROENVIRONMENT-ACTIVATED DRUG-BINDER CONJUGATES, AND USES RELATED THERETO | AVACTA LIFE SCIENCES, LIMITED (GB) | 2021-11-18 | — | — | US | disclosed |
| US-20190209525-A1 | DASH INHIBITORS, AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353652-A1 | TUMOR MICROENVIRONMENT-ACTIVATED DRUG-BINDER CONJUGATES, AND USES RELATED THERETO | CD47, VCAM1, CD44 | PREP 2346/4885PSMB5 3631/4885FAP 193/4885 |
| US-11583516-B2 | Dash inhibitors, and uses related thereto | PCNA, CD2BP2, CCNO | PREP 1101/4885PSMB5 3540/4885FAP 794/4885 |
| US-20190209525-A1 | DASH INHIBITORS, AND USES RELATED THERETO | CD2BP2, PCNA, CD2 | PREP 996/4885PSMB5 3583/4885FAP 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.