Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156246 | 0.95 | ALDH1A1 (0.30) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL21155817 | 0.93 | ALDH1A1 (0.32) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL24637708 | 0.92 | — | — | |
| SCHEMBL19917228 | 0.91 | EGFR (0.36) | EGFRRETKDRCTRC | |
| SCHEMBL21156751 | 0.89 | ALDH1A1 (0.31) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL21156739 | 0.89 | ALDH1A1 (0.32) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL20043994 | 0.89 | KMT2A (0.35) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL24637705 | 0.88 | EGFR (0.36) | EGFRRETKDRCTRC | |
| SCHEMBL21155807 | 0.88 | KMT2A (0.31) | ALDH1A1MAPTTHRBHPGDRECQL | |
| SCHEMBL21776032 | 0.87 | ALDH1A1 (0.32) | ALDH1A1MAPTTHRBHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214581-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214581-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | OCIAD2, OCIAD1, EED | ALDH1A1 2581/4885MAPT 33/4885THRB 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.