Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890863 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL4569189 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL27925834 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL226196 | 0.76 | HSD17B10 (0.76) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL4019720 | 0.72 | HSD17B10 (0.70) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL4889683 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL30873471 | 0.71 | HSD17B10 (0.68) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL8398635 | 0.71 | HSD17B10 (0.68) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL4313850 | 0.71 | HSD17B10 (0.68) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL10907729 | 0.71 | HSD17B10 (0.58) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |