Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.41 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.41 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4F8 | P98187 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964420 | 0.82 | GRM2 (0.43) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL19964415 | 0.76 | GRM2 (0.39) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11081174 | 0.73 | BRD4 (0.58) | BRD4GRM2ALDH1A1LMNAHDAC4 | |
| SCHEMBL21157358 | 0.72 | BRD4 (0.56) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2020140 | 0.69 | ABL1 (0.59) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29489425 | 0.69 | CYP3A4 (0.73) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL196765 | 0.69 | CYP3A4 (0.73) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1483077 | 0.68 | ABL1 (0.53) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29628977 | 0.67 | CYP3A4 (0.77) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.67 | CYP3A4 (0.70) | BRD4CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | EZH2, IKZF2, SUZ12 | BRD4 151/4885CYP1A2 3428/4885CYP3A4 1623/4885 |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | EZH2, IKZF2, SUZ12 | BRD4 151/4885CYP1A2 3428/4885CYP3A4 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.