SCHEMBL2020140

SCHEMBL2020140

COc1cccc(-c2ccccc2-c2cccc(OC)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.59
ABCB1 P08183 2/20 0.59
BCR P11274 2/20 0.59
CYP1A1 P04798 2/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2E1 P05181 2/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C8 P10632 2/20 0.57
CYP2D6 P10635 2/20 0.57
CYP2A6 P11509 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP4B1 P13584 2/20 0.57
CYP2B6 P20813 2/20 0.57
CYP3A5 P20815 2/20 0.57
CYP2A7 P20853 2/20 0.57
CYP3A7 P24462 2/20 0.57
CYP2F1 P24903 2/20 0.57
CYP2C18 P33260 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP2J2 P51589 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3455245 0.96 ABL1 (0.60) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL13211663 0.96 ABL1 (0.60) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL10023268 0.90 ACHE (0.64) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL2876291 0.89 CLK4 (0.56) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL5849737 0.88 CYP1A1 (0.65) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL321834 0.88 CASR (0.57) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL14118224 0.87 CD274 (0.60) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL995091 0.86 ALDH1A1 (0.52) ABL1ABCB1BCRCYP1A1CYP1A2
SCHEMBL7579760 0.86 CASR (0.58) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8
SCHEMBL20786847 0.86 BRD4 (0.49) ABL1ABCB1BCRCYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
EP-2185532-B1 BENZO-FUSED THIOPHENE COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORP (US) 2016-11-09 EP disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SK MATERIALS JNC CO., LTD. (KR) 2011-09-08 US disclosed
WO-2011081451-A2 TRI-PHENYL COMPOUNDS AND ORGANIC ELECTRO-LUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2011-07-07 WO disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-20110108814-A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-05-12 US disclosed
US-20110108814-A1 POLYMER COMPOUND, NET-LIKE POLYMER COMPOUND PRODUCED BY CROSSLINKING THE POLYMER COMPOUND, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-05-12 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SLC25A11, ELAVL1, SLC26A3 ABL1 2107/4885ABCB1 1029/4885BCR 2763/4885
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC ABL1 540/4885ABCB1 312/4885BCR 682/4885
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SLC25A11, ELAVL1, SLC26A3 ABL1 2107/4885ABCB1 1029/4885BCR 2763/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC ABL1 716/4885ABCB1 801/4885BCR 1757/4885
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEAD2 ABL1 983/4885ABCB1 1057/4885BCR 2089/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 ABL1 983/4885ABCB1 1057/4885BCR 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.