SCHEMBL2115790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31672571	1.00	KDR (0.75)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL13755242	1.00	KDR (0.75)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL15202708	0.93	KDR (0.79)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL15202709	0.92	KDR (0.77)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL15202704	0.87	KDR (0.84)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL5396558	0.87	KDR (0.57)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	Sunitinib SCHEMBL2726232	0.87	KDR (0.95)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL142711	0.87	KDR (0.71)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL18651190	0.87	KDR (0.85)	KDRPRKAA1PRKAA2PDGFRBFGFR1
	SCHEMBL144383	0.86	KDR (0.74)	KDRPRKAA1PRKAA2PDGFRBFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.