Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803028 | 1.00 | LMNA (0.41) | LMNAPOLBSMN1; SMN2MAPTIRAK4 | |
| SCHEMBL28308732 | 0.89 | PARP15 (0.46) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL30803074 | 0.89 | PARP15 (0.46) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL21156963 | 0.88 | LMNA (0.40) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL28561966 | 0.82 | KMT2A (0.47) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL21157492 | 0.81 | POLB (0.41) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL29898969 | 0.81 | POLB (0.41) | LMNAPOLBSMN1; SMN2MAPTCTPS1 | |
| SCHEMBL28548656 | 0.81 | MAPT (0.42) | LMNAPOLBSMN1; SMN2MAPTIRAK4 | |
| SCHEMBL19451492 | 0.79 | PRSS1 (0.51) | LMNAPOLBSMN1; SMN2MAPTPARP1 | |
| SCHEMBL22121012 | 0.77 | PRSS1 (0.46) | LMNAPOLBSMN1; SMN2MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658992-A | Benzimidazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | disclosed |
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2019134705-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |