Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889072 | 0.85 | STING1 (0.45) | STING1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29012734 | 0.85 | STING1 (0.45) | STING1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29406354 | 0.85 | STING1 (0.45) | STING1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL22121412 | 0.85 | STING1 (0.38) | STING1 | |
| SCHEMBL23077453 | 0.84 | STING1 (0.40) | STING1 | |
| SCHEMBL21158094 | 0.82 | STING1 (0.36) | STING1PDE4B | |
| SCHEMBL28630481 | 0.81 | PARP15 (0.38) | STING1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21158117 | 0.81 | PDE4D (0.39) | STING1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL24611698 | 0.81 | STING1 (0.35) | STING1 | |
| SCHEMBL23095443 | 0.81 | STING1 (0.37) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019134705-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |