Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917169 | 0.85 | GAA (0.30) | GAA | |
| SCHEMBL21159564 | 0.78 | — | — | |
| SCHEMBL19917182 | 0.74 | ABCB1 (0.32) | — | |
| SCHEMBL19917095 | 0.74 | HTT (0.31) | — | |
| SCHEMBL28302322 | 0.72 | PDE8B (0.35) | PDE8BTLR7 | |
| SCHEMBL19917111 | 0.71 | NPSR1 (0.36) | — | |
| SCHEMBL19916990 | 0.69 | JAK3 (0.42) | — | |
| SCHEMBL21159272 | 0.69 | JAK3 (0.42) | — | |
| SCHEMBL20595698 | 0.69 | PDE4A (0.34) | PDE8BGAA | |
| SCHEMBL21159616 | 0.66 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |