Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428024 | 0.86 | HRH1 (0.50) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL248607 | 0.86 | HRH1 (0.50) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL18751372 | 0.81 | HRH3 (0.42) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL11800372 | 0.79 | HRH1 (0.42) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL21386868 | 0.79 | HRH1 (0.42) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL11815522 | 0.79 | ALDH1A1 (0.44) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL28985167 | 0.79 | HRH1 (0.50) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL28985180 | 0.79 | HRH1 (0.50) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL10810253 | 0.79 | HRH1 (0.50) | HRH1LMNASMN1; SMN2MAPTLIN28A | |
| SCHEMBL6666747 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136298-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DISEASES INVOLVING ACIDIC OR HYPOXIC DISEASED TISSUES | Cybrexa, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |