Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926598 | 0.79 | TDP1 (0.47) | PDE10ANPC1RAB9AKDM4EEGFR | |
| SCHEMBL11868826 | 0.74 | TERT (0.49) | PDE10ANPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL15286657 | 0.74 | NPC1 (0.55) | PDE10ANPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL27971030 | 0.73 | BRD4 (0.42) | PDE10ANPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL3756445 | 0.72 | KDM4E (0.45) | PDE10ANPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL21160614 | 0.72 | APP (0.40) | KDM4EEGFRTDP1L3MBTL1MAP4K4 | |
| SCHEMBL8863408 | 0.72 | DYRK1A (0.49) | PDE10ANPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL21160452 | 0.71 | MAPT (0.41) | NPC1RAB9AEGFRL3MBTL1MAP4K4 | |
| SCHEMBL21037411 | 0.71 | APP (0.47) | NPC1RAB9AKDM4EEGFRTDP1 | |
| SCHEMBL21160460 | 0.70 | PDE10A (0.43) | PDE10ANPC1RAB9AEGFRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011658-A1 | METHOD FOR DETECTING AND QUANTIFYING RNA | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2023011657-A1 | METHOD FOR DETECTING AND QUANTIFYING RNA | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | PDE10A 3340/4885NPC1 1998/4885RAB9A 1864/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | PDE10A 3370/4885NPC1 1881/4885RAB9A 3069/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | PDE10A 3340/4885NPC1 1998/4885RAB9A 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.