SCHEMBL21160620

SCHEMBL21160620

CN(CCO)c1ccc(C#C/C=C(\C#N)C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
APP P05067 1/20 0.36
SLC16A3 O15427 2/20 0.35
SLC16A1 P53985 2/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21037409 0.84 L3MBTL1 (0.36) L3MBTL1APPMEN1ALDH1A1MAPT
SCHEMBL22295750 0.79 L3MBTL1 (0.40) L3MBTL1APP
SCHEMBL21160479 0.79 CISD1 (0.55) SLC16A3SLC16A1ALDH1A1
SCHEMBL21036838 0.77 L3MBTL1 (0.41) L3MBTL1APPMEN1ALDH1A1MAPT
SCHEMBL5776081 0.71 L3MBTL1 (0.43) L3MBTL1APPALDH1A1KMT2A
SCHEMBL21160410 0.71 MAPT (0.64) APPSLC16A3SLC16A1MEN1ALDH1A1
SCHEMBL21037019 0.69 MAPT (0.43) APPMEN1ALDH1A1MAPTKMT2A
SCHEMBL21160095 0.69 L3MBTL1 (0.41) L3MBTL1APPALDH1A1MAPT
SCHEMBL8707328 0.68 L3MBTL1 (0.46) L3MBTL1APPMEN1ALDH1A1MAPT
SCHEMBL12694260 0.68 L3MBTL1 (0.43) L3MBTL1APPMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209437-B2 Fluorescent probe and preparation method and use thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) 2021-12-28 US disclosed
US-20190187144-A1 FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190187144-A1 FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF HNRNPF, HNRNPUL2, RAB5IF L3MBTL1 616/4885APP 2001/4885SLC16A3 3971/4885
US-11209437-B2 Fluorescent probe and preparation method and use thereof HNRNPF, HNRNPUL2, RAB5IF L3MBTL1 616/4885APP 2001/4885SLC16A3 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.