Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155625 | 0.88 | PARP1 (0.70) | PARP1 | |
| SCHEMBL29435084 | 0.85 | PARP1 (1.00) | PARP1 | |
| SCHEMBL12256417 | 0.85 | PARP1 (1.00) | PARP1 | |
| SCHEMBL21160074 | 0.79 | PARP1 (0.48) | PARP1 | |
| SCHEMBL14980870 | 0.76 | PARP1 (1.00) | PARP1 | |
| SCHEMBL14356190 | 0.70 | MAP3K9 (0.52) | PARP1 | |
| SCHEMBL14356200 | 0.70 | MAP3K9 (0.52) | PARP1 | |
| SCHEMBL14346098 | 0.69 | PARP1 (0.57) | PARP1 | |
| SCHEMBL12846284 | 0.69 | PARP1 (0.64) | PARP1 | |
| SCHEMBL12786101 | 0.68 | PARP1 (0.56) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136298-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DISEASES INVOLVING ACIDIC OR HYPOXIC DISEASED TISSUES | Cybrexa, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |