Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313935 | 0.86 | APP (0.41) | APPMAPTSLC16A3SLC16A1 | |
| SCHEMBL21234685 | 0.84 | APP (0.43) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22784074 | 0.80 | KDM4E (0.40) | ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL22314051 | 0.78 | DNM1 (0.43) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22314181 | 0.78 | APP (0.72) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22295850 | 0.76 | MAPT (0.39) | MAPTALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL22784086 | 0.76 | KDM4E (0.40) | MAPTMEN1KMT2AALDH1A1SLC16A3 | |
| SCHEMBL21234738 | 0.74 | ATM (0.35) | MAPTALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL22295772 | 0.73 | SLC16A3 (0.46) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15859154 | 0.73 | MAPT (0.72) | APPMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | APP 2001/4885MAPT 2624/4885MEN1 2099/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | APP 2264/4885MAPT 3407/4885MEN1 1100/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | APP 2001/4885MAPT 2624/4885MEN1 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.