Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 3/20 | 0.36 |
| ▸ | ADH1C | P00326 | 3/20 | 0.36 |
| ▸ | ADH1A | P07327 | 3/20 | 0.36 |
| ▸ | ADH7 | P40394 | 3/20 | 0.36 |
| ▸ | ADH4 | P08319 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763807 | 1.00 | TSHR (0.46) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL21078061 | 0.93 | TSHR (0.52) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL18714894 | 0.91 | TSHR (0.50) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL17378045 | 0.91 | TSHR (0.50) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL16362458 | 0.91 | TSHR (0.50) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL9206506 | 0.91 | TSHR (0.50) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL172661 | 0.91 | TSHR (0.46) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL21498936 | 0.88 | TSHR (0.46) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL9407527 | 0.87 | TSHR (0.52) | TSHRALDH1A1CYP3A4ANPEPERAP2 | |
| SCHEMBL30994817 | 0.87 | TSHR (0.50) | TSHRALDH1A1CYP3A4ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198903-A1 | NOVEL SUBSTITUTED FLUORINATED N-PROPYL-PYRROLIDINE AND N‑PROPYL-AZETIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
| US-10726701-B2 | Devices, systems and methods for locating and interacting with medicament delivery systems | KALEO, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190206220-A1 | DEVICES, SYSTEMS AND METHODS FOR LOCATING AND INTERACTING WITH MEDICAMENT DELIVERY SYSTEMS | KALEO, INC. (US) | 2019-07-04 | — | — | US | disclosed |