⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292261 | 0.74 | — | — | |
| SCHEMBL10042745 | 0.71 | CNR2 (0.38) | — | |
| SCHEMBL26525044 | 0.70 | SIGMAR1 (0.39) | — | |
| SCHEMBL25641637 | 0.69 | — | — | |
| SCHEMBL25641649 | 0.69 | — | — | |
| SCHEMBL18856492 | 0.66 | — | — | |
| SCHEMBL18856636 | 0.66 | — | — | |
| SCHEMBL19294281 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL20705654 | 0.65 | HTR2C (0.41) | — | |
| SCHEMBL19004551 | 0.65 | SLC6A4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336684-B2 | Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators | BRISTOL=MYERS SQUIBB COMPANY (US) | 2019-07-02 | — | — | US | disclosed |