Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.37 |
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001637 | 0.95 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL999449 | 0.92 | ALDH1A1 (0.61) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL16114276 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL26268695 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HSD17B10MAOAKDM1AMAOB | |
| Oxirane SCHEMBL8981894 | 0.84 | ALDH1A1 (0.75) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL21422778 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAOAKDM1AMAOB | |
| SCHEMBL26269820 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL998688 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL998687 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTNPSR1KDM4E | |
| SCHEMBL26248383 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4245756-A1 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2019136244-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ABNORMAL CELLULAR PROLIFERATION | G1 THERAPEUTICS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |