Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720608 | 0.84 | TSHR (0.69) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL4057568 | 0.79 | MAPT (0.68) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL2302971 | 0.79 | MAPT (0.68) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL16051336 | 0.79 | ALDH1A1 (0.67) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL1583125 | 0.78 | SMN1; SMN2 (0.59) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL2951307 | 0.78 | MEN1 (0.72) | HTTTSHRHPGDSMN1; SMN2MEN1 | |
| SCHEMBL10330512 | 0.78 | HTT (0.86) | HTTTSHRRECQLHPGDKMT2A | |
| SCHEMBL3456393 | 0.78 | KMT2A (0.72) | HTTHPGDMEN1KMT2AGLA | |
| SCHEMBL2303658 | 0.78 | HTT (0.58) | HTTTSHRRECQLHPGDSMN1; SMN2 | |
| SCHEMBL5166136 | 0.78 | SMN1; SMN2 (0.59) | HTTTSHRRECQLHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508477-A1 | C5AR ANTAGONISTS | ChemoCentryx, Inc. (US) | 2019-07-10 | — | — | EP | disclosed |