Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945889 | 0.90 | MEN1 (0.43) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL21106913 | 0.88 | MEN1 (0.46) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL26018455 | 0.88 | MEN1 (0.46) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL24927410 | 0.88 | MEN1 (0.46) | MEN1KMT2APOLBCNR1CNR2 | |
| SCHEMBL22821424 | 0.87 | MEN1 (0.47) | MEN1KMT2APOLBEPHX2SMN1; SMN2 | |
| SCHEMBL23225828 | 0.86 | MEN1 (0.43) | MEN1KMT2APOLBSMN1; SMN2HSD17B10 | |
| SCHEMBL5066367 | 0.85 | MEN1 (0.50) | MEN1KMT2APOLBEPHX2SMN1; SMN2 | |
| SCHEMBL22821556 | 0.82 | KMT2A (0.55) | MEN1KMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL18389543 | 0.81 | MEN1 (0.39) | MEN1KMT2ATDP1CNR1CNR2 | |
| SCHEMBL23789741 | 0.81 | KMT2A (0.49) | MEN1KMT2APOLBEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209572-A1 | BIFUNCTIONAL ANTIFUNGAL AGENTS AND METHODS OF TREATING FUNGAL INFECTION | MERCK SHARP & DOHME CORP. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209572-A1 | BIFUNCTIONAL ANTIFUNGAL AGENTS AND METHODS OF TREATING FUNGAL INFECTION | ERG28, PAICS, BAK1 | MEN1 2404/4885KMT2A 1118/4885TDP1 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.