SCHEMBL21164095

SCHEMBL21164095

CCc1ccc(N(c2cc(C(C)C)c3ccc4c(N(c5ccc(CC)c(C)c5)c5cccc6c5oc5ccccc56)cc(C(C)C)c5ccc2c3c54)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.32
CNR2 P34972 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4084522 0.96 ALOX5 (0.32) MEN1KMT2AMAPTCNR2GPR55
SCHEMBL18624831 0.92
SCHEMBL4088896 0.86 POLB (0.31) MAPT
SCHEMBL26262103 0.84 CNR2 (0.33) MEN1KMT2ACNR2GPR55
SCHEMBL17573100 0.84 MAOB (0.36) MAPTALOX5
SCHEMBL4084424 0.83 ALOX5 (0.32) MEN1KMT2AMAPTALOX5
SCHEMBL4088969 0.83 GGPS1 (0.30)
SCHEMBL26246513 0.82 CNR2 (0.30) CNR2GPR55
SCHEMBL4088897 0.82 NPC1 (0.33) MEN1KMT2AMAPTALOX5
SCHEMBL879273 0.82 TNKS (0.39) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 US disclosed
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214563-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 MEN1 862/4885KMT2A 596/4885MAPT 988/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 MEN1 862/4885KMT2A 596/4885MAPT 988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.