Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 4/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186337 | 0.90 | MAPK8 (0.64) | RENMAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL21164378 | 0.89 | REN (0.60) | RENMAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL30439967 | 0.87 | CMA1 (0.55) | RENCMA1 | |
| SCHEMBL30616203 | 0.85 | REN (0.60) | RENMAPK8MAPK9MAPK10CMA1 | |
| SCHEMBL30440130 | 0.84 | CMA1 (0.57) | RENCMA1 | |
| SCHEMBL30440351 | 0.84 | CMA1 (0.55) | RENCMA1 | |
| SCHEMBL10061557 | 0.84 | CMA1 (0.55) | RENCMA1 | |
| SCHEMBL30051241 | 0.80 | REN (0.55) | RENMAPK8MAPK9MAPK10CMA1 | |
| SCHEMBL24372015 | 0.80 | CMA1 (0.51) | RENCMA1 | |
| SCHEMBL13323714 | 0.80 | CMA1 (0.51) | RENCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-11 | — | — | US | disclosed |
| US-10730913-B1 | Antimicrobial analogues of gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-04 | — | — | US | disclosed |
| US-10351602-B1 | Antimicrobial analogues of gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730913-B1 | Antimicrobial analogues of gramicidin S | GMPS, AAAS, GNPDA1 | REN 1941/4885MAPK8 3924/4885MAPK9 3393/4885 |
| US-10351602-B1 | Antimicrobial analogues of gramicidin S | GMPS, AAAS, GNPDA1 | REN 1941/4885MAPK8 3924/4885MAPK9 3393/4885 |
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | GMPS, AAAS, GNPDA1 | REN 1941/4885MAPK8 3924/4885MAPK9 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.