SCHEMBL21165034

SCHEMBL21165034

Cc1cc(C)c(Nc2ccc(C(c3ccc(Nc4c(C)cc(C)cc4C)cc3)c3ccc(NC4CCCCC4Cl)c4ccccc34)cc2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 10/20 0.35
IDO1 P14902 1/20 0.33
TP53 P04637 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PYGL P06737 2/20 0.30
CYP2C9 P11712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165369 0.84 KDM1A (0.31) IDO1
SCHEMBL20251315 0.84
SCHEMBL21165049 0.82 F9 (0.37) TP53
SCHEMBL21165036 0.81 RAPGEF4 (0.47) RAPGEF4
SCHEMBL17953198 0.80 TP53 (0.32) TP53RXFP1
SCHEMBL17953188 0.79 RXFP1 (0.32) TP53RXFP1
SCHEMBL20251306 0.79 CYP26A1 (0.32) TP53RXFP1
SCHEMBL21165316 0.77 RAPGEF4 (0.43) RAPGEF4
SCHEMBL17953156 0.77
SCHEMBL21165197 0.77 RAPGEF4 (0.42) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 RAPGEF4 3390/4885IDO1 3157/4885TP53 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.