⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167514 | 0.64 | — | — | |
| SCHEMBL14149232 | 0.62 | — | — | |
| SCHEMBL24159337 | 0.62 | — | — | |
| SCHEMBL8349136 | 0.61 | — | — | |
| SCHEMBL12233197 | 0.60 | MTNR1A (0.41) | — | |
| SCHEMBL828267 | 0.60 | MTNR1A (0.41) | — | |
| SCHEMBL14753281 | 0.60 | MTNR1A (0.41) | — | |
| SCHEMBL23119662 | 0.60 | — | — | |
| SCHEMBL12409572 | 0.60 | — | — | |
| SCHEMBL12409568 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119765-B1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-07-17 | — | — | EP | disclosed |