Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165833 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL21165842 | 0.70 | TACR1 (0.36) | — | |
| SCHEMBL12448246 | 0.68 | NR1H2 (0.49) | — | |
| SCHEMBL21165827 | 0.66 | ESR1 (0.33) | — | |
| SCHEMBL19686595 | 0.66 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL14290751 | 0.66 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL2940886 | 0.62 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL12449192 | 0.62 | CHRNB2 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL12449191 | 0.61 | SCN9A (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL21165823 | 0.61 | CHRNB2 (0.48) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | KCNJ11, KCNJ2, KCNJ1 | CHRNB2 504/4885CHRNA4 365/4885 |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | CHRNB2 504/4885CHRNA4 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.