⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367684 | 0.82 | SIGMAR1 (0.30) | — | |
| SCHEMBL6659778 | 0.82 | SIGMAR1 (0.30) | — | |
| SCHEMBL22210750 | 0.79 | SIGMAR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6663231 | 0.77 | — | — | |
| SCHEMBL6665913 | 0.76 | — | — | |
| SCHEMBL24316208 | 0.73 | SIGMAR1 (0.30) | — | |
| SCHEMBL10267303 | 0.73 | EPHX1 (0.39) | — | |
| SCHEMBL20063377 | 0.73 | SIGMAR1 (0.30) | — | |
| SCHEMBL20880512 | 0.72 | — | — | |
| SCHEMBL6888123 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774064-B2 | Potassium channel modulators | CADENT THERAPEUTICS, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190218200-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2019-07-18 | — | — | US | disclosed |