SCHEMBL21166682

SCHEMBL21166682

CC(C)(C)C(C)(c1ccc(O)cc1)c1ccc(O)cc1.CC(C)(CCc1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.55
ESR2 Q92731 7/20 0.55
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SHBG P04278 1/20 0.47
ESRRG P62508 5/20 0.41
ESRRB O95718 2/20 0.41
SLC6A2 P23975 2/20 0.41
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
CYP3A4 P08684 1/20 0.41
AR P10275 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR6 P50406 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA2 P00918 1/20 0.39
TMEM97 Q5BJF2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18481 0.91 ESR1 (0.64) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL22921016 0.86 LMNA (0.59) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL22921109 0.80 ESR1 (0.51) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL313073 0.79 ESR1 (0.62) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL29003915 0.78 PTGS1 (0.49) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL19690377 0.76 ESR1 (0.59) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL219016 0.76 ESR1 (0.56) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL11307434 0.75 ESR1 (0.57) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL25037508 0.74 ESR1 (0.49) ESR1ESR2MEN1KMT2ASHBG
SCHEMBL31589391 0.74 ESR1 (0.54) ESR1ESR2MEN1KMT2ASHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10359171-B2 Heat ray absorbing lamp cover SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-23 US disclosed