Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098872 | 0.83 | KDM4C (0.61) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL244632 | 0.81 | KDM4C (0.70) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL30785801 | 0.81 | KDM4C (0.70) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL310266 | 0.81 | TDP1 (0.62) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL220890 | 0.81 | KDM4C (0.70) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL11786508 | 0.79 | KDM4C (0.68) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL9469391 | 0.79 | KDM4E (0.52) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL11786496 | 0.79 | KDM4C (0.68) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| SCHEMBL8067971 | 0.79 | KDM4E (0.52) | KDM4EKDM4CALDH1A1TDP1MEN1 | |
| Water SCHEMBL11483542 | 0.79 | TDP1 (0.60) | KDM4EKDM4CALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019137381-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW LABORATORIES, INC. (CN) | 2019-07-18 | — | — | WO | disclosed |