Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11483542 | 0.98 | TDP1 (0.60) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL11098872 | 0.84 | KDM4C (0.61) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL244632 | 0.83 | KDM4C (0.70) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL2139056 | 0.83 | KDM4E (0.70) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL220890 | 0.83 | KDM4C (0.70) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL30785801 | 0.83 | KDM4C (0.70) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL1687197 | 0.82 | TDP1 (0.67) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| SCHEMBL1330970 | 0.82 | TDP1 (0.67) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL11786496 | 0.81 | KDM4C (0.68) | TDP1SIRT3KDM4EALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL11786508 | 0.81 | KDM4C (0.68) | TDP1SIRT3KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148139-A2 | METABOLITE-BASED PARTICLES AND COMPOSITIONS THEREOF FOR PREVENTING AND TREATING NEUROLOGICAL DISEASES AND DISORDERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2024-07-11 | — | — | WO | claimed |
| CN-103609593-B | Agricultural composition with function of sugar increase and coloring of fruit | Hebei Academy of Forestry Science | 2014-12-03 | — | — | CN | claimed |
| CN-103609593-A | Agricultural composition with function of sugar increase and coloring of fruit | Hebei Academy of Forestry Science | 2014-03-05 | — | — | CN | claimed |
| EP-2635556-A2 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2013-09-11 | — | — | EP | claimed |
| CN-102633715-A | Inhibitor of mitogen protein kinase p38 and preparation method of inhibitor | WUXI ALLNATURE NUTRITION HEALTH CARE PRODUCT TECHNOLOGY CO LTD | 2012-08-15 | — | — | CN | claimed |
| WO-2012061418-A2 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | claimed |
| CN-101765425-A | Use of benzamide derivatives for the treatment of CNS disorders | HOFFMANN LA ROCHE | 2010-06-30 | — | — | CN | claimed |
| EP-4127157-B1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | ENCODIA INC (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025143877-A1 | DERIVATIVE COMPOUND COMPRISING AMINO NICOTINAMIDE STRUCTURE AND ANTIFUNGAL PHARMACEUTICAL COMPOSITION COMPRISING SAME | (주)앰틱스바이오 | 2025-07-03 | — | — | WO | disclosed |
| WO-2025143305-A1 | DERIVATIVE COMPOUND COMPRISING AMINO NICOTINAMIDE STRUCTURE AND ANTIFUNGAL PHARMACEUTICAL COMPOSITION CONTAINING SAME | (주)앰틱스바이오 | 2025-07-03 | — | — | WO | disclosed |
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |
| US-11993585-B2 | Poly-ADP ribose polymerase (PARP) inhibitors | MITOBRIDGE, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| US-4885291-A | 1-carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0324562-A1 | 1-Carba(dethia)-3-cephem derivatives | ELI LILLY AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4129643-A | Method for rapid screening of teratogenic agents | CLAYTON RUTH M | 1978-12-12 | — | — | US | disclosed |
| US-4067741-A | Hardening photographic layers containing silver halide with a 1-sulphonyl-4-amino-pyridinium salt | AGFA-GEVAERT, A.G. (DT) | 1978-01-10 | — | — | US | disclosed |
| US-3970663-A | Certain amino-nicotinamide derivatives | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICAL (FR) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993585-B2 | Poly-ADP ribose polymerase (PARP) inhibitors | PARP1, PARP2, PARP11 | TDP1 40/4885SIRT3 147/4885KDM4E 2486/4885 |
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | PARP14, PARP15, PARP11 | TDP1 120/4885SIRT3 33/4885KDM4E 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.