SCHEMBL21166974

SCHEMBL21166974

Cn1c2cc(-c3cccc4c3sc3ccccc34)ccc2c(=O)c2cc3c(cc21)c(=O)c1ccc(-c2cccc4c2sc2ccccc24)cc1n3C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.52
PRKDC P78527 5/20 0.47
L3MBTL1 Q9Y468 5/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ATM Q13315 1/20 0.43
POLB P06746 2/20 0.42
RXFP1 Q9HBX9 2/20 0.42
GAA P10253 1/20 0.42
PARP14 Q460N5 1/20 0.41
PIK3CD O00329 1/20 0.38
BRD4 O60885 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
KCNH2 Q12809 1/20 0.38
BRDT Q58F21 1/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987501 0.93 ALOX5 (0.52) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL25987247 0.87 ALOX5 (0.57) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL20987315 0.85 ALOX5 (0.43) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL17432320 0.84 ALOX5 (0.53) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL21023302 0.82 PARP14 (0.45) ALOX5PRKDCL3MBTL1ATMPOLB
SCHEMBL20987311 0.82 ALOX5 (0.42) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL15785772 0.82 ALOX5 (0.59) ALOX5PRKDCL3MBTL1RXFP1PARP14
SCHEMBL15747051 0.80 ALOX5 (0.57) ALOX5PRKDCL3MBTL1PARP14PIK3CD
SCHEMBL15216402 0.79 ALOX5 (0.62) ALOX5PRKDCL3MBTL1NPC1RAB9A
SCHEMBL15785767 0.78 ALOX5 (0.54) ALOX5PRKDCL3MBTL1PARP14PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed