Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23047605 | 0.84 | ESR1 (0.49) | FPR2ESR1SMN1; SMN2 | |
| SCHEMBL22356858 | 0.82 | FPR2 (0.39) | FPR2ALPGPLAAALPLSMN1; SMN2 | |
| SCHEMBL12037553 | 0.80 | ALPG (0.47) | FPR2ALPGPLAAALPLSMN1; SMN2 | |
| SCHEMBL21167198 | 0.80 | FPR2 (0.50) | FPR2ALPGPLAAALPL | |
| SCHEMBL21539525 | 0.79 | FPR2 (0.42) | FPR2ALPGPLAAALPLSMN1; SMN2 | |
| SCHEMBL21539580 | 0.79 | FPR2 (0.41) | FPR2ALPGPLAAALPLCA12 | |
| SCHEMBL21167203 | 0.79 | MCL1 (0.38) | FPR2ALPGPLAAALPLSMN1; SMN2 | |
| SCHEMBL19967938 | 0.78 | ESR1 (0.42) | ESR1SMN1; SMN2 | |
| SCHEMBL21167269 | 0.78 | FPR2 (0.41) | FPR2ALPGPLAAALPLHSP90AA1 | |
| SCHEMBL21167223 | 0.78 | FPR2 (0.34) | FPR2ALPGPLAAALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511003-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2019-07-17 | — | — | EP | disclosed |