Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167414 | 0.88 | MET (0.53) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL24591122 | 0.87 | MET (0.44) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167616 | 0.86 | MET (0.55) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167610 | 0.86 | MET (0.54) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167608 | 0.86 | MET (0.41) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167483 | 0.85 | MET (0.36) | METPDE10ASYK | |
| SCHEMBL22475958 | 0.84 | MET (0.42) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22475671 | 0.84 | MET (0.44) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167397 | 0.83 | MET (0.46) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21167714 | 0.82 | MET (0.44) | METSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795573-B1 | CERTAIN TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |