Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.57 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977106 | 0.91 | AGTR2 (0.62) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL21125234 | 0.91 | AGTR2 (0.51) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL25000031 | 0.90 | AGTR2 (0.51) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL21167925 | 0.89 | AGTR2 (0.55) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL21168140 | 0.89 | AGTR2 (0.59) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL30206864 | 0.89 | PPARG (0.59) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL7018017 | 0.89 | PPARG (0.59) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL13465074 | 0.87 | AGTR2 (0.59) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL21168165 | 0.86 | AGTR2 (0.54) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL15157487 | 0.86 | AGTR2 (0.55) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673274-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | JUBILANT GENERICS LTD (IN) | 2019-07-17 | — | — | EP | disclosed |