SCHEMBL21168167

SCHEMBL21168167

c1ccc(-c2cc(-c3cccnc3)cc(-c3cccc(-c4cc(-c5cccnc5)cc(-c5cccnc5)c4)c3)c2)nc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 9/20 0.73
GRM5 P41594 2/20 0.56
PIM1 P11309 1/20 0.52
PIM2 Q9P1W9 1/20 0.52
CYP3A4 P08684 2/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52
MEN1 O00255 1/20 0.51
PSIP1 O75475 1/20 0.51
AXL P30530 1/20 0.51
MKNK1 Q9BUB5 1/20 0.51
MKNK2 Q9HBH9 1/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
TP53 P04637 1/20 0.51
PKM P14618 1/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CYP19A1 P11511 2/20 0.50
CYP17A1 P05093 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17721056 0.97 CYP2A6 (0.69) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18134294 0.97 CYP2A6 (0.69) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18134272 0.97 CYP2A6 (0.69) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18134274 0.97 CYP2A6 (0.69) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18650176 0.97 CYP2A6 (0.69) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL24492855 0.97 CYP2A6 (0.73) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL11965543 0.97 CYP2A6 (0.73) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL12068486 0.96 CYP2A6 (0.79) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18650183 0.95 CYP2A6 (0.67) CYP2A6GRM5PIM1PIM2CYP3A4
SCHEMBL18650178 0.95 CYP2A6 (0.67) CYP2A6GRM5PIM1PIM2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190221749-A1 CHARGE TRANSPORT MATERIAL, COMPOUND, DELAYED FLUORESCENT MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT SLC43A1, SLC7A5, SLC39A3 CYP2A6 3530/4885GRM5 1505/4885PIM1 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.