SCHEMBL21168847

SCHEMBL21168847

c1ccc(-c2nc3ccccc3nc2-c2ccc(-n3c4ccccc4c4cc5c6ccc7ccccc7c6n(-c6ccc7ccccc7c6)c5cc43)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
KDM4E B2RXH2 3/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 3/20 0.34
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
PRSS1 P07477 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
DHODH Q02127 1/20 0.33
TSHR P16473 1/20 0.32
PDE10A Q9Y233 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168880 0.96 L3MBTL1 (0.36) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL21168848 0.96 L3MBTL1 (0.36) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL21168881 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMLMNAALDH1A1
SCHEMBL21168849 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMLMNAALDH1A1
SCHEMBL22722259 0.92 L3MBTL1 (0.41) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL21716746 0.92 L3MBTL1 (0.35) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL21168729 0.91 HPGD (0.35) HPGDKDM4EALDH1A1F2F10
SCHEMBL22141262 0.91 KDM4E (0.37) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL22141290 0.91 KDM4E (0.37) HPGDL3MBTL1KDM4EATMLMNA
SCHEMBL21168854 0.90 L3MBTL1 (0.39) HPGDL3MBTL1KDM4EATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328152-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-10-21 US disclosed
US-20200058882-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-02-20 US disclosed
US-20190355912-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2019-11-21 US disclosed
US-20190221752-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190221752-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME EPCAM, OR10J3, L1CAM HPGD 4308/4885L3MBTL1 960/4885KDM4E 763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.