⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23369742 | 0.88 | — | — | |
| SCHEMBL23080516 | 0.88 | — | — | |
| SCHEMBL21621805 | 0.88 | — | — | |
| SCHEMBL23080515 | 0.88 | — | — | |
| SCHEMBL19982473 | 0.88 | — | — | |
| SCHEMBL24631081 | 0.88 | — | — | |
| SCHEMBL19982472 | 0.88 | — | — | |
| SCHEMBL21169319 | 0.60 | HSD17B10 (0.37) | — | |
| SCHEMBL20859129 | 0.60 | — | — | |
| SCHEMBL19309630 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654794-B2 | Fused tricyclic Γ-amino acid derivative, preparation method therefor, and medical use thereof | SICHUAN HAISO PHARMACEUTICAL CO., LTD. (CN) | 2020-05-19 | — | — | US | disclosed |
| US-20190218172-A1 | FUSED TRICYCLIC GAMMA-AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | SICHUAN HAISO PHARMACEUTICAL CO., LTD. (CN) | 2019-07-18 | — | — | US | disclosed |