Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631162 | 0.89 | — | — | |
| SCHEMBL21622219 | 0.89 | — | — | |
| SCHEMBL21169331 | 0.60 | — | — | |
| SCHEMBL15974369 | 0.59 | CYP2C9 (0.47) | HSD17B10 | |
| SCHEMBL30410546 | 0.58 | — | — | |
| SCHEMBL20859129 | 0.57 | — | — | |
| SCHEMBL10516694 | 0.56 | — | — | |
| SCHEMBL19309630 | 0.55 | — | — | |
| SCHEMBL17856067 | 0.55 | — | — | |
| SCHEMBL17856128 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654794-B2 | Fused tricyclic Γ-amino acid derivative, preparation method therefor, and medical use thereof | SICHUAN HAISO PHARMACEUTICAL CO., LTD. (CN) | 2020-05-19 | — | — | US | disclosed |
| US-20190218172-A1 | FUSED TRICYCLIC GAMMA-AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | SICHUAN HAISO PHARMACEUTICAL CO., LTD. (CN) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218172-A1 | FUSED TRICYCLIC GAMMA-AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | SLC38A7, BCAT2, SLC6A11 | HSD17B10 1045/4885 |
| US-10654794-B2 | Fused tricyclic Γ-amino acid derivative, preparation method therefor, and medical use thereof | SLC38A7, BCAT2, BCAT1 | HSD17B10 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.