SCHEMBL21169494

SCHEMBL21169494

Brc1ccc(-c2c3ccc4c(c3nc3c2ccc2ccccc23)CCC=C4)cc1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31006107 0.81 CYP1A1 (0.59) CYP1A1CYP1A2CYP1B1
SCHEMBL14994072 0.81 CYP1A1 (0.59) CYP1A1CYP1A2CYP1B1
SCHEMBL18904922 0.79 CYP1A1 (0.57) CYP1A1CYP1A2CYP1B1
SCHEMBL19007319 0.79 HSD17B1 (0.32) CYP1A1CYP1A2CYP1B1
SCHEMBL19186073 0.73 CYP1A1 (0.35) CYP1A1CYP1A2CYP1B1
SCHEMBL15004492 0.73 HPRT1 (0.48) CYP1A1CYP1A2CYP1B1
SCHEMBL18904925 0.73 CYP1B1 (0.54) CYP1A1CYP1A2CYP1B1
SCHEMBL1893653 0.72 HSD17B10 (0.41) CYP1A2CYP1B1
SCHEMBL15004489 0.72 HPRT1 (0.46) CYP1A1CYP1A2CYP1B1
SCHEMBL29396923 0.72 HPRT1 (0.46) CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2786435-B1 Compounds NOVALED GMBH (DE) 2019-07-17 EP disclosed