Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902047 | 0.86 | ALDH1A1 (0.35) | CHRNB2CHRNB4CHRNA4ALDH1A1TSHR | |
| SCHEMBL8902794 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL7333962 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL22648830 | 0.79 | CHRM2 (0.30) | — | |
| SCHEMBL13244549 | 0.78 | TP53 (0.32) | — | |
| SCHEMBL3040832 | 0.78 | TP53 (0.32) | — | |
| SCHEMBL8625751 | 0.77 | — | — | |
| SCHEMBL23515745 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13243736 | 0.69 | — | — | |
| SCHEMBL4873108 | 0.69 | ALDH1A1 (0.39) | CHRNB2CHRNB4CHRNA4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283577-B1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-07-17 | — | — | EP | disclosed |