Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15380 | 0.92 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29362516 | 0.92 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL276066 | 0.89 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL714505 | 0.84 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL18780250 | 0.81 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2725437 | 0.81 | NPC1 (0.36) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL28981814 | 0.80 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL4975463 | 0.80 | NPC1 (0.36) | NPC1RAB9APOLBLMNAKDM4E | |
| Bisoctrizole SCHEMBL25391231 | 0.80 | NPC1 (0.37) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL16264135 | 0.80 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10653588-B2 | Composition for protecting the keratin materials from sun | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
| US-20190216692-A1 | COMPOSITION FOR PROTECTING THE KERATIN MATERIALS FROM SUN | L'OREAL (FR) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216692-A1 | COMPOSITION FOR PROTECTING THE KERATIN MATERIALS FROM SUN | KRT18, SERPINA3, SERPINA2 | NPC1 3345/4885RAB9A 2824/4885POLB 489/4885 |
| US-10653588-B2 | Composition for protecting the keratin materials from sun | KRT18, SERPINA3, SERPINA2 | NPC1 3345/4885RAB9A 2824/4885POLB 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.