Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977017 | 0.92 | NPC1 (0.36) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL15380 | 0.87 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29362516 | 0.87 | NPC1 (0.48) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL4978494 | 0.84 | NPC1 (0.34) | NPC1RAB9AKDM4EALDH1A1CYP2C9 | |
| SCHEMBL4978624 | 0.83 | PTPN1 (0.31) | KDM4ECYP3A4 | |
| SCHEMBL276066 | 0.82 | NPC1 (0.46) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL4977389 | 0.82 | ALDH1A1 (0.33) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL4977461 | 0.81 | NPC1 (0.33) | NPC1RAB9APOLBLMNA | |
| SCHEMBL13028238 | 0.81 | NPC1 (0.34) | NPC1RAB9APOLBLMNA | |
| SCHEMBL21169728 | 0.80 | NPC1 (0.43) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131921-A1 | SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS | ISDIN S.A. (ES) | 2008-11-06 | — | — | WO | disclosed |