Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 7/20 | 0.55 |
| ▸ | RXRB | P28702 | 6/20 | 0.55 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997458 | 0.87 | TSHR (0.63) | TP53TSHRCA12CA1CA2 | |
| SCHEMBL22734016 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL30610360 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL15521764 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL864660 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL23202431 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL21133280 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL21133337 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL142861 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 | |
| SCHEMBL30610361 | 0.85 | EGFR (0.72) | EGFRRXRARXRBRXRGBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3300797-B1 | POROUS COORDINATION POLYMER AND GAS STORAGE USING THE SAME | PANASONIC IP MAN CO LTD (JP) | 2019-07-17 | — | — | EP | disclosed |