SCHEMBL142861

SCHEMBL142861

O=C(O)c1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccc(C(=O)O)cc5)cc4)cc(-c4ccc(-c5ccc(C(=O)O)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.72
RXRA P19793 7/20 0.71
RXRB P28702 6/20 0.71
TP53 P04637 1/20 0.67
TSHR P16473 1/20 0.67
BCL2L1 Q07817 1/20 0.65
BAD Q92934 1/20 0.65
RXRG P48443 2/20 0.63
SRD5A2 P31213 1/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15521764 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL18687046 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL30610360 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL30610361 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL864660 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL23202431 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL21133337 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL21133280 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL22734016 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR
SCHEMBL27037008 1.00 EGFR (0.72) EGFRRXRARXRBTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4585600-A1 RETICULAR DESIGN AND DEVELOPMENT OF HIGHLY POROUS METAL-ORGANIC FRAMEWORKS FOR GAS AND VAPOR SORPTION APPLICATIONS Special Account for Research Funds of University of Crete (SARF UoC) (GR) 2025-07-16 EP claimed
US-12300821-B2 Anode binder for lithium rechargeable battery, anode binder including cured compound of the same anode binder LG CHEM, LTD. (KR) 2025-05-13 US claimed
CN-119601901-A Separator, preparation method of polymer nanosheets, battery and energy storage device 厦门海辰储能科技股份有限公司 2025-03-11 CN claimed
US-20240409561-A1 Tunable Rare Earth Metal-Organic Frameworks for Complex Optical Tags NNSA 2024-12-12 US claimed
US-20240269659-A1 FRUSTRATED LEWIS PAIR-IMPREGNATED POROUS MATERIALS AND USES THEREOF UNIVERSITY OF SOUTH FLORIDA 2024-08-15 US claimed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP claimed
CN-118022556-B CuZn-C-loaded PEI modified PVDF self-cleaning film and preparation method and application thereof 四川大学 2024-06-11 CN claimed
CN-118022556-A CuZn-C-loaded PEI modified PVDF self-cleaning film and preparation method and application thereof 四川大学 2024-05-14 CN claimed
US-20240009613-A1 CO2 CAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES AGARWAL, Shantanu 2024-01-11 US claimed
CN-117209789-A Preparation method and application of hydrogen bond self-assembled microporous organic framework 安徽工业大学 2023-12-12 CN claimed
CN-110052244-B Preparation method of metal organic complex material for gathering and sensing malachite green 天津科技大学 2022-04-01 CN claimed
WO-2022040072-A1 CO2 CAPTURE SORBENTS WITH LOW REGENERATION TEMPERATURE AND HIGH DESORPTION RATES SUSTEON INC. (US) 2022-02-24 WO claimed
CN-111804346-A Method for rapidly preparing metal organic layer material and application 中国人民解放军国防科技大学 2020-10-23 CN claimed
US-20140163111-A1 POROUS BIOMOLECULE-CONTAINING METAL-ORGANIC FRAMEWORKS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-06-12 US claimed
US-8658562-B2 Method for hydrothermal preparation of metal-organic framework crystallised porous aluminium carboxylates Centre National de la Recherche Scientifique—CNRS (FR) 2014-02-25 US claimed
EP-2467388-A2 OPEN METAL ORGANIC FRAMEWORKS WITH EXCEPTIONAL SURFACE AREA AND HIGH GAS STRORAGE CAPACITY The Regents of The University of California (US) 2012-06-27 EP claimed
EP-2260048-B1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST CENTRE NAT RECH SCIENT (FR) 2012-03-28 EP claimed
US-20120055880-A1 METHOD FOR HYDROTHERMAL PREPARATION OF METAL-ORGANIC FRAMEWORK CRYSTALLISED POROUS ALUMINIUM CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2012-03-08 US claimed
WO-2011038208-A2 OPEN METAL ORGANIC FRAMEWORKS WITH EXCEPTIONAL SURFACE AREA AND HIGH GAS STRORAGE CAPACITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-03-31 WO claimed
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST Centre National De La Recherche Scientifique - CNR S (FR) 2011-03-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST MITF, SLCO2B1, SLCO2A1 EGFR 1575/4885RXRA 1691/4885RXRB 2183/4885
US-20240269659-A1 FRUSTRATED LEWIS PAIR-IMPREGNATED POROUS MATERIALS AND USES THEREOF LPO, GPX4, NCF1 EGFR 2954/4885RXRA 2558/4885RXRB 3646/4885
US-20140163111-A1 POROUS BIOMOLECULE-CONTAINING METAL-ORGANIC FRAMEWORKS SLCO2B1, SLCO4C1, SLCO2A1 EGFR 708/4885RXRA 4446/4885RXRB 4264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.