Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 17/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213799 | 0.84 | OPRK1 (0.56) | OPRK1HTTLMNAPRNPMAPT | |
| SCHEMBL16944615 | 0.82 | OPRK1 (1.00) | OPRK1 | |
| SCHEMBL6103100 | 0.82 | OPRK1 (0.54) | OPRK1HTTLMNAPRNPMAPT | |
| SCHEMBL21170839 | 0.80 | OPRK1 (0.74) | OPRK1 | |
| SCHEMBL18994669 | 0.76 | OPRK1 (0.59) | OPRK1 | |
| SCHEMBL31195809 | 0.75 | HTT (0.43) | OPRK1HTTLMNAPRNPMAPT | |
| SCHEMBL2711135 | 0.75 | HTT (0.43) | OPRK1HTTLMNAPRNPMAPT | |
| SCHEMBL17316555 | 0.73 | HTT (0.41) | OPRK1HTTLMNAPRNPMAPT | |
| SCHEMBL21171821 | 0.72 | OPRK1 (0.59) | OPRK1 | |
| SCHEMBL21170914 | 0.71 | OPRK1 (0.51) | OPRK1HTTLMNAPRNPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884978-B1 | NOVEL KAPPA OPIOID LIGANDS | SCRIPPS RESEARCH INST (US) | 2019-07-17 | — | — | EP | disclosed |