Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21172016 | 0.98 | IDO1 (0.33) | IDO1ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL18609088 | 0.91 | IDO1 (0.30) | IDO1 | |
| SCHEMBL5586278 | 0.87 | IDO1 (0.37) | IDO1ALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL36010 | 0.79 | CA1 (0.42) | ALDH1A1LMNAKDM4EMEN1TP53 | |
| Pharacine SCHEMBL3876076 | 0.79 | CA1 (0.42) | ALDH1A1LMNAKDM4EMEN1TP53 | |
| SCHEMBL28704246 | 0.79 | CA1 (0.42) | ALDH1A1LMNAKDM4EMEN1TP53 | |
| SCHEMBL3873588 | 0.79 | CA1 (0.42) | ALDH1A1LMNAKDM4EMEN1TP53 | |
| SCHEMBL28713686 | 0.79 | CA1 (0.42) | ALDH1A1LMNAKDM4EMEN1TP53 | |
| SCHEMBL2483184 | 0.77 | CA1 (0.40) | ALDH1A1LMNAMEN1TP53MAPT | |
| SCHEMBL3174046 | 0.77 | CA1 (0.40) | ALDH1A1LMNAMEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141576-B1 | FIBER-REINFORCED COMPOSITES MADE WITH MULTI-PART THERMOPLASTIC POLYMERS | JOHNS MANVILLE (US) | 2020-07-01 | — | — | EP | disclosed |
| US-20190217554-A1 | FIBER-REINFORCED COMPOSITES MADE WITH MULTI-PART THERMOPLASTIC POLYMERS | JOHNS MANVILLE | 2019-07-18 | — | — | US | disclosed |