SCHEMBL21172087

SCHEMBL21172087

O=C(O)c1c(N=C=S)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ POLB P06746 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ PLEC Q15149 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ ALPL P05186 1/20 0.51
▸ ALPI P09923 1/20 0.51
▸ ALPG P10696 1/20 0.51
▸ CA9 Q16790 14/20 0.48
▸ CA1 P00915 12/20 0.48
▸ CA2 P00918 12/20 0.48
▸ CA12 O43570 6/20 0.46
▸ DNASE1L3 Q13609 1/20 0.46
▸ PRMT1 Q99873 1/20 0.46
▸ CDC25A P30304 1/20 0.44
▸ CDC25B P30305 1/20 0.44
▸ CDC25C P30307 1/20 0.44
▸ GNG2 P59768 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13273546 0.82 USP2 (0.67) USP2MEN1POLBKMT2AATM
SCHEMBL2755000 0.80 USP2 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL15138753 0.79 USP2 (0.56) USP2MEN1POLBKMT2AATM
SCHEMBL29591827 0.77 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL29781098 0.77 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL107875 0.77 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL23841197 0.76 USP2 (0.55) USP2MEN1POLBKMT2AATM
SCHEMBL8451224 0.76 USP2 (0.74) USP2MEN1POLBKMT2AATM
SCHEMBL7591292 0.76 USP2 (0.74) USP2MEN1POLBKMT2AATM
SCHEMBL8427558 0.75 USP2 (0.64) USP2MEN1POLBKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804862-B1 METHODS OF MAKING AND USING NANOSTRUCTURES UNIV MINNESOTA (US) 2019-07-17 — — EP disclosed
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