SCHEMBL8427558

SCHEMBL8427558

O=C(O)c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
POLB P06746 2/20 0.64
ATM Q13315 1/20 0.64
PLEC Q15149 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.61
ALPL P05186 1/20 0.59
ALPI P09923 1/20 0.59
ALPG P10696 1/20 0.59
CDC25A P30304 1/20 0.56
CDC25B P30305 1/20 0.56
CDC25C P30307 1/20 0.56
GNG2 P59768 1/20 0.53
GNB1 P62873 1/20 0.53
DNASE1L3 Q13609 1/20 0.49
PRMT1 Q99873 1/20 0.49
AKR1B1 P15121 3/20 0.49
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828559 0.88 MEN1 (0.58) USP2MEN1KMT2APOLBATM
SCHEMBL22043216 0.82 MEN1 (0.56) USP2MEN1KMT2APOLBATM
SCHEMBL19615424 0.81 USP2 (0.62) USP2MEN1KMT2APOLBATM
SCHEMBL12559919 0.81 USP2 (0.62) USP2MEN1KMT2APOLBATM
SCHEMBL19465298 0.81 USP2 (0.53) USP2MEN1KMT2APOLBATM
SCHEMBL13273546 0.80 USP2 (0.67) USP2MEN1KMT2APOLBATM
SCHEMBL2775968 0.79 USP2 (0.63) USP2MEN1KMT2APOLBATM
SCHEMBL20254033 0.79 USP2 (0.77) USP2MEN1KMT2APOLBATM
SCHEMBL7824274 0.79 USP2 (0.77) USP2MEN1KMT2APOLBATM
SCHEMBL10098714 0.79 USP2 (0.76) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5972987-A DETECTION LICE WITH DYE LORI FOX REID (US) 1999-10-26 US claimed
US-5972987-A DETECTION LICE WITH DYE LORI FOX REID (US) 1999-10-26 US disclosed