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SCHEMBL21172208

SCHEMBL21172208

CCC(=O)NCCCCC(NC(=O)CCC(NC(=O)C(CS(=O)(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.52
▸ NOD1 Q9Y239 6/20 0.51
▸ FOLH1 Q04609 1/20 0.46
▸ EPHX2 P34913 3/20 0.45
▸ FNTA P49354 1/20 0.42
▸ FNTB P49356 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21172279 0.90 GLP1R (0.48) GLP1RNOD1FOLH1EPHX2FNTA
SCHEMBL21172323 0.89 GLP1R (0.48) GLP1RNOD1FOLH1FNTAFNTB
SCHEMBL12518529 0.89 GLP1R (0.48) GLP1RNOD1FOLH1EPHX2FNTA
SCHEMBL24179874 0.89 GLP1R (0.48) GLP1RNOD1FOLH1
SCHEMBL19270619 0.89 GLP1R (0.48) GLP1RNOD1FOLH1EPHX2FNTA
SCHEMBL21172243 0.88 NOD1 (0.58) GLP1RNOD1FOLH1EPHX2
SCHEMBL20414814 0.88 NOD1 (0.58) GLP1RNOD1FOLH1EPHX2
SCHEMBL23365799 0.88 NOD1 (0.58) GLP1RNOD1FOLH1EPHX2
SCHEMBL27436076 0.88 NOD1 (0.58) GLP1RNOD1FOLH1EPHX2
SCHEMBL21172236 0.87 GLP1R (0.43) GLP1RNOD1EPHX2FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981282-B1 GROWTH HORMONE COMPOUND FORMULATION NOVO NORDISK HEALTHCARE AG (CH) 2020-11-04 — — EP disclosed
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 — — EP disclosed