Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21233252 | 0.87 | PREP (0.41) | PREPDPP4GPR119CHRM2CHRM1 | |
| SCHEMBL22643283 | 0.87 | PREP (0.41) | PREPDPP4GPR119CHRM2CHRM1 | |
| SCHEMBL16064424 | 0.87 | PREP (0.41) | PREPDPP4GPR119CHRM2CHRM1 | |
| SCHEMBL18373188 | 0.86 | CTSC (0.45) | CTSKCTSC | |
| SCHEMBL16075199 | 0.86 | CTSC (0.45) | CTSKCTSC | |
| SCHEMBL22643220 | 0.80 | CTSC (0.42) | PREPCTSKCTSC | |
| SCHEMBL16645163 | 0.80 | CTSC (0.42) | PREPCTSKCTSC | |
| SCHEMBL16064417 | 0.80 | CTSC (0.42) | PREPCTSKCTSC | |
| SCHEMBL20384135 | 0.77 | PREP (0.39) | PREPDPP4GPR119CHRM2CHRM1 | |
| SCHEMBL21172930 | 0.77 | PREP (0.40) | PREPDPP4GPR119CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511331-A1 | SPIROCYCLIC INHIBITORS OF CATHEPSIN C | Boehringer Ingelheim International GmbH (DE) | 2019-07-17 | — | — | EP | disclosed |