Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL16335546 | 1.00 | SLC7A5 (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Tyrosine SCHEMBL10722796 | 0.92 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28150507 | 0.89 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28151458 | 0.89 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL27980641 | 0.87 | SLC7A5 (0.41) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL27597221 | 0.86 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL25375940 | 0.86 | ALPI (0.44) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL22501395 | 0.86 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL3630630 | 0.85 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1675409 | 0.85 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2851429-B1 | PROTEIN AND PROTEIN CONJUGATE FOR DIABETES TREATMENT, AND APPLICATIONS THEREOF | ADDA BIOTECH INC (CN) | 2019-07-24 | — | — | EP | claimed |
| CN-109180802-A | Compound, composition with hypoglycemic effect and application thereof | 爱德迪安（北京）生物技术有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-107739409-A | Albumen, protein conjugate and its application for treating diabetes | 爱德迪安（北京）生物技术有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-104302772-A | Protein for diabetes treatment, protein conjugate and application thereof | ADDA BIOTECH INC | 2015-01-21 | — | — | CN | claimed |
| CN-104114575-A | Compound with hypoglycemic effect, composition and application thereof | AIDE DI AN BEIJING BIOTECH CO LTD | 2014-10-22 | — | — | CN | claimed |
| CN-104011070-A | Compound with hypoglycemic effect, composition and application thereof | ADDA BIOTECH INC | 2014-08-27 | — | — | CN | claimed |
| CN-104114575-B | Compound with hypoglycemic effect, composition and application thereof | 爱德迪安（北京）生物技术有限公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-109180802-A | Compound, composition with hypoglycemic effect and application thereof | 爱德迪安（北京）生物技术有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-107739409-A | Albumen, protein conjugate and its application for treating diabetes | 爱德迪安（北京）生物技术有限公司 | 2018-02-27 | — | — | CN | disclosed |
| CN-104302772-B | Protein for diabetes treatment, protein conjugate and application thereof | 爱德迪安（北京）生物技术有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104302772-A | Protein for diabetes treatment, protein conjugate and application thereof | ADDA BIOTECH INC | 2015-01-21 | — | — | CN | disclosed |
| CN-104114575-A | Compound with hypoglycemic effect, composition and application thereof | AIDE DI AN BEIJING BIOTECH CO LTD | 2014-10-22 | — | — | CN | disclosed |
| CN-104011070-A | Compound with hypoglycemic effect, composition and application thereof | ADDA BIOTECH INC | 2014-08-27 | — | — | CN | disclosed |